depurination

The spontaneous cleavage of the N glycosidic link between purine bases and deoxyribose in DNA. Depurination of DNA results in the loss of a purine from the DNA backbone and DNA strand breakage. Such DNA lesions are often the result of ionizing radiation, free radicals, or alkylating reagents that destabilize the N-glycosidic bond. Left unchecked, they have the potential to cause mutagenesis and carcinogenesis. Depurination is also a well-known…

List of Biology Words Starting with D

…eus Dentatorubro-pallidoluysian atrophy (DRPLA) Denticle pattern deoxynucleotide deoxyribonucleic acid deoxyribonucleotide triphosphate Deoxyribose depauperate fauna dependent variable Depolarisation depolarization depurination derepressed desert desmosome determinant determination deterministic detritivore detritus detrivore deuterostomes development deviation di- dia- Diabetes Insipidous Diabetes Mellitus diagnose d…